People from all across the globe have been fighting against the coronavirus (COVID-19) pandemic for the last three years. The pandemic that has its roots in China has been a headache for everyone. It was a matter of huge fear during the initial days, but the situation has come under control since the invention of COVID vaccines.
Vaccines have played a very important role in reducing the COVID transmission and also healing COVID-affected people. A lot of vaccines have been made and used after their trials and examinations. Oxford University’s coronavirus vaccine clinical trial was also very important, and we’ll look into its explanation through this article.
Keep reading this article to learn more about the Coronavirus vaccine clinical trial explanation from Oxford University and much more!
When was the Interim trial data released by Oxford University?
The University of Oxford, in collaboration with AstraZeneca plc, announced the interim trial data from the third (III) phase of its trials on November 23, 2020. These trials showed results about the effectiveness of its candidate coronavirus vaccine, ChAdOx1 nCoV-2019.
According to the results, this coronavirus vaccine is effective at preventing COVID-19 and also provides a high level of protection against the deadly virus. Professor Andrew Pollard was the Director of the Oxford Vaccine Group and Chief Investigator of the Oxford Vaccine Trial.
Noteworthy points of the trials:-
- The Phase III analysis of Oxford included 131 COVID-19 cases, and it showed that the vaccine is 70.4% effective (when combining data from two dosing regimens).
- When seen individually, the two dose regimens vaccine efficiency was 90% and 62% respectively.
- Early results indicated that the vaccine would be able to reduce the transmission of the virus.
- Crucially, the vaccine can be easily administered in the already existing healthcare system. It can be easily stored at domestic fridge temperature (2-8 degree Celsius).
What was the main objective of this research?
The main objective of this research was to test the COVID-19 vaccine on humans to check its effectiveness as well as the consequences of the vaccine. To check for the same, the vaccine was used on people who volunteered to be a part of this research. It also aimed to determine the protection of this new vaccine, ChAdOx1 nCoV-19, from COVID-19 across all different age groups. It also includes explanations about the protection features and the ability of the vaccine to produce stronger immune responses to the virus.
The Oxford vaccine (ChAdOx1 nCoV-19) has been made from a virus, which is a weakened version of an adenovirus (a common cold virus). However, it has been changed genetically, making it impossible for the virus to grow in humans.
Explanation of the study by Oxford University
Brief explanation of the Coronavirus vaccine clinical trial of Oxford university is as per the following:
Stage 1: The Stage I trials of the coronavirus vaccine study began in April 2020 in healthy volunteers. Over 1,000 immunizations were accomplished at first and continued later.
Stage 2: The Stage II trials of the Coronavirus vaccine study recruited up to 10,260 adults and children, including multiple partner organizations nationwide. Three age groups were made: 56–69 years, more than 70 years, and the group of 5–12 years.
Stage 3: The Stage III of the Coronavirus vaccine study was to check the vaccine’s performance in people over 18 to determine how the vaccine performed to protect people from the COVID-19 virus. If any of the participants developed symptoms of COVID-19 during the vaccine study, they were instructed to contact a member of the clinical team for an examination
The COVID pandemic’s peakedness has varied with time, but it has still not left the human race at peace. China is currently facing the most disastrous situation due to COVID, as there has been a sudden surge in cases there. The recent COVID outbreak in China is the worst the country has faced since the start of this virus.
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